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| News
| | | Pfizer back at the top?; Abating counterfeit medicine fears; Roche sets sight on Genentech; Unfavourable trial results go unpublished
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| PAT: HPLC on the horizon?
| | | By
Michael Kraft
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George Barringer
| | | PAT guidance has been available from FDA for more than 4 years, but there have been no apparent breakthroughs in large-scale upstream production. Will companies consider using on?line chromatography to change this?
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| Ensuring raw material quality
| | | By
Sheelagh Halsey
| | | This month's expert examines the most appropriate technique for checking raw material quality. What technique would you recommend for quality checking of raw materials?
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| Quantifying experience in powder processing
| | | By
Tim Freeman
| | | Enshrined in the concept of Quality by Design is the premise that optimized pharmaceutical manufacturing requires detailed understanding of products and processes. With this in mind, many benefits can be achieved by combining modern powder characterization techniques with real processing experience.
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| LC–MS/MS method for the determination of Vitamin D3 in human plasma
| | | By
Xuejun Peng
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Rong Yi
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Amara Pinnawala
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Sarah Ostonal
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Eliot Chung
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Grace van der Gugten
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Bernard Nutley
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David Gray
| | | An LC–MS/MS method for the quantitative determination of vitamin D3 in human plasma has been developed and validated with positive atmospheric chemical ionization sources.
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| Building on the promise of biotech
| | | By
Faiz Kermani
| | | The productivity of the pharma industry has been declining for several years. Could biotechnology reinvigorate drug development?
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| Goodbye and hello
| | | By
Fedra Pavlou
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Bibiana Campos-Seijo
| | | This month's editor's comment.
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