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Jul 4, 2009

Dosage Forms

Formulation effects on the thermomechanical properties and permeability of free films and coating films

01 June 2009

Understanding a formulation's variable effects on its properties, especially film permeability, is key to designing a robust formulation and reducing variation of a finished product.

Narrowing the gap between clinical capsule formulations and commercial film-coated tablets

01 May 2009

Based on formulation simplicity and blinding capability, hard gelatin capsules are preferrable compared with other oral solid dosage forms, including tablets, in the early clinical phases of drug development.

Orally disintegrating tablets: the path to improved patient compliance and enhanced life cycle management

01 May 2009

Orally disintegrating tablets offer numerous advantages compared with traditional tablets and capsules, and can be an effective solution for developing line extensions of currently marketed therapies.

Fast dissolving disintegrating tablets with isomalt

01 February 2009

During the past years, there has been increasing demand for fast dissolving disintegrating tablets (FDDTs), such as orally disintegrating tablets (ODTs) and sublinguals.

Application-related properties of a new fast dispersible excipient

01 January 2009

A new excipient for orally disintegrating tablets not only imparts superior tablet characteristics, but has the added advantage of allowing users to maintain full control over their formulations, manufacturing processes and intellectual property.

Meeting the Challenge of Scaling Up High Dose ODTs

17 December 2008

The application of oral disintegrating technologies to higher dose actives is a natural extension of this ease of delivery dosage form.

The influence of concomitant use of alcoholic beverages on hypromellose matrix tablets

01 December 2008

Research shows that both drug prescription and alcohol consumption increase within the elderly population. It is, therefore, necessary to fully understand the impact of alcohol consumption on solid oral dosage forms, especially extended release formulations.

PVA copolymer: the new coating agent

01 October 2008

The use of PVA copolymer-based film can solve the problems associated with lack of film adhesion... to tablets containing large amounts of waxy excipient or a lubricant.

Creating PVA copolymer capsules

01 June 2008

When drugs are encapsulated, electrification (the electrostatic charge of the capsule) may sometimes cause problems, such as capsule adhesion during transportation or dispersion of the capsule content in the filling process.

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