01 July 2009
By:Riccardo Bonfichi, Giulia Cloralio, Andrea Rainoldi
Cefaclor is a β-lactam cephalosporin antibiotic that has a wide particle size distribution. Because of the nonporous nature of the material, the specific surface area value accounts for a significant amount of fine particles possibly present in the samples under analysis.
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01 April 2009
By:Paul Kippax
An expert on diffraction systems offers insight on particle size specifications and analysis.
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01 April 2009
By:Daniel Burnett, Nishil Malde, Daryl Williams
Even small amounts of amorphous materials can have a significant effect on the drug product. Are gravimetric vapour sorption techniques an effective solution to characterize amorphous materials?
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01 March 2009
By:Sheelagh Halsey
This month's expert examines the most appropriate technique for checking raw material quality. What technique would you recommend for quality checking of raw materials?
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01 December 2008
The expanding role for X-ray powder diffraction in the pharmaceutical industry.
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01 September 2008
By:Justine Bentley
As counterfeiters become more cunning and technologically advanced, spotting their handiwork is increasingly difficult. Can surface analysis techniques be used to outwit them?
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01 June 2008
By:Jim Hillier
There are two ways in which 'difficult' samples are usually categorized: either by the problems posed by the physical nature of the post-vivo sample matrix containing the chemical entity to be analysed, or...
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01 April 2008
By:Justine Bentley
Our company is involved in developing and manufacturing APIs that can be utilized with drug-eluting stents (DES). Despite ensuring constancy in pharmaceutical composition, we are experiencing issues with variations in drug release during in vitro studies. We are working closely with a stent manufacturer to develop the system, but could surface analysis techniques investigate the problem further?
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